Case Identification
Case ID Number
Tumor Type
Body region
Position within the bone
Periosteal reaction
Benign or Malignant
Clinical case information
Case presentation
A 12 year old boy from Sicily had a history of mild trauma to the right leg approximately one month prior to presentation. He presented with mild pain and a mass near the right knee.
Radiological findings:
AP and lateral radiographs of the distal femur, an axial and coronal MRI, and a CT scan image are shown. A radiograph and CT scan of the chest were negative (One abnormality or questionable nodule of uncertain significance was seen in the left lower lobe that we will ignore for the purposes of this exercise). A whole body bone scan showed abnormal uptake in the right distal femur but no other abnormality.
Laboratory results:
The alkaline phosphatase was 1174 (normal 240 -760).
Special Features of this Case:
1) What is the most likely diagnosis?
2) What is the stage of the tumor using the Enneking or Musculoskeletal Tumor Society's surgical staging system?
3a) This patient will undergo peroperative chemotherapy. How can the chemotherapy help determine his prognosis?
3b)What pre-operative blood tests have prognostic significance in this tumor?
2) What is the stage of the tumor using the Enneking or Musculoskeletal Tumor Society's surgical staging system?
3a) This patient will undergo peroperative chemotherapy. How can the chemotherapy help determine his prognosis?
3b)What pre-operative blood tests have prognostic significance in this tumor?
Image
Case ID Number
Image Types
Image modality
Tumor Name
Tumor Type
Benign or Malignant
Body region
Bone name
Location in the bone
periosteal reaction
position within the bone
Tumor behavior
Tumor density